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Lysosomal trafficking regulator

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Protein-coding gene in the species Homo sapiens
lysosomal trafficking regulator
Identifiers
SymbolLYST
Alt. symbolsCHS1
NCBI gene1130
HGNC1968
OMIM606897
RefSeqNM_000081
UniProtQ99698
Other data
LocusChr. 1 q42.1-42.2
Search for
StructuresSwiss-model
DomainsInterPro

Lysosomal trafficking regulator is a vesicular transport protein associated with Chédiak–Higashi syndrome.

In melanocytic cells LYST gene expression may be regulated by MITF.

References

  1. Hoek KS, Schlegel NC, Eichhoff OM, et al. (2008). "Novel MITF targets identified using a two-step DNA microarray strategy". Pigment Cell Melanoma Res. 21 (6): 665–76. doi:10.1111/j.1755-148X.2008.00505.x. PMID 19067971.

External links

Membrane protein: vesicular transport proteins (TC 1F)
Synaptic vesicle
SNARE
Q-SNARE
R-SNARE
Synaptotagmin
Other
COPI
COPII
RME/Clathrin
Caveolae
Other/ungrouped
Vesicle formation
Adaptor protein complex 1:
Adaptor protein complex 2:
Adaptor protein complex 3:
Adaptor protein complex 4:
BLOC-1:
BLOC-2:
BLOC-3:
Coats:
Small GTPase
Other
See also vesicular transport protein disorders


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