Properidine - Misplaced Pages

Chemical compound Pharmaceutical compound

Properidine
Clinical data

Other names	Ipropethidine
ATC code	none
Legal status
Legal status	AU: S9 (Prohibited substance) BR: Class A1 (Narcotic drugs) CA: Schedule I DE: Anlage I (Authorized scientific use only) UK: Class A US: Schedule I UN: Psychotropic Schedule I
Identifiers
IUPAC name isopropyl 1-methyl-4-phenylpiperidine-4-carboxylate
CAS Number	561-76-2
PubChem CID	62373
ChemSpider	56161
UNII	R1493W1CJ0
KEGG	D13025
CompTox Dashboard (EPA)	DTXSID20204644
ECHA InfoCard	100.008.385
Chemical and physical data
Formula	C₁₆H₂₃NO₂
Molar mass	261.365 g·mol
3D model (JSmol)	Interactive image
SMILES O=C(OC(C)C)C2(c1ccccc1)CCN(C)CC2
InChI InChI=1S/C16H23NO2/c1-13(2)19-15(18)16(9-11-17(3)12-10-16)14-7-5-4-6-8-14/h4-8,13H,9-12H2,1-3H3 Key:XJKQCILVUHXVIQ-UHFFFAOYSA-N
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Properidine is an opioid, an analgesic, and the isopropyl analog of pethidine. Properidine is under international control and is listed in the United States under the Controlled Substances Act (1970) as a Schedule I substance. It is a narcotic, with an Administrative Controlled Substances Code Number (ACSCN) of 9644 and a 2 gramme annual aggregate manufacturing quota as of 2014. The salt in use is hydrochloride, with a free base conversion ratio of 0.88.

References

Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.
Morrison AL, Rinderknecht H (1950). "302. Synthetic analgesics. Part V. Compounds related to pethidine". Journal of the Chemical Society (Resumed): 1467. doi:10.1039/JR9500001467.
"Quotas - 2014". Diversion Control Division. U.S. Department of Justice, Drug Enforcement Administration.