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| PubChem = 5517 | | PubChem = 5517 | ||
| DrugBank = | | DrugBank = | ||
| KEGG = D02317 | |||
| C=19|H=15|F=3|N=4|O=3 | | C=19|H=15|F=3|N=4|O=3 | ||
| molecular_weight = 404.34 g/mol | | molecular_weight = 404.34 g/mol |
Revision as of 01:15, 21 January 2011
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Formula | C19H15F3N4O3 |
Molar mass | 404.34 g/mol g·mol |
Tosufloxacin is a fluoroquinolone antibiotic. It has a controversial safety profile in relation to other fluoroquinolones. It is associated with severe thrombocytopenia and nephritis, and hepatotoxicity. It is sold in Japan under the brand name Ozex.
See also
References
- Rubinstein, E. (2001). "History of quinolones and their side effects". Chemotherapy. 47 Suppl 3: 3–8, discussion 44–8. PMID 11549783.
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Antibacterials that inhibit nucleic acid (J01E, J01M) | |||||||||||||||||
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Antifolates (inhibit bacterial purine metabolism, thereby inhibiting DNA and RNA synthesis) |
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Quinolones (inhibit bacterial topoisomerase and/or DNA gyrase, thereby inhibiting DNA replication) |
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Anaerobic DNA inhibitors |
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RNA synthesis |
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