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Levobunolol

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This is an old revision of this page, as edited by CheMoBot (talk | contribs) at 10:42, 21 October 2011 (Updating {{drugbox}} (changes to verified fields - updated 'CAS_number_Ref') per Chem/Drugbox validation (report errors or bugs)). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Revision as of 10:42, 21 October 2011 by CheMoBot (talk | contribs) (Updating {{drugbox}} (changes to verified fields - updated 'CAS_number_Ref') per Chem/Drugbox validation (report errors or bugs))(diff) ← Previous revision | Latest revision (diff) | Newer revision → (diff) Pharmaceutical compound
Levobunolol
Clinical data
Trade namesBetagan
AHFS/Drugs.comMonograph
MedlinePlusa686011
Pregnancy
category
  • C
Routes of
administration
Topical (eye drops)
ATC code
Legal status
Legal status
Pharmacokinetic data
Elimination half-life20 hours
Identifiers
IUPAC name
  • (S)-5-{oxy}-3,4-dihydronaphthalen-1(2H)-one
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC17H25NO3
Molar mass291.385 g/mol g·mol
3D model (JSmol)
SMILES
  • O=C2c1cccc(OC(O)CNC(C)(C)C)c1CCC2
InChI
  • InChI=1S/C17H25NO3/c1-17(2,3)18-10-12(19)11-21-16-9-5-6-13-14(16)7-4-8-15(13)20/h5-6,9,12,18-19H,4,7-8,10-11H2,1-3H3/t12-/m0/s1
  • Key:IXHBTMCLRNMKHZ-LBPRGKRZSA-N
  (what is this?)  (verify)

Levobunolol (AK-Beta, Liquifilm, Betegan) is a non-selective beta blocker. It is used topically to manage glaucoma.

References

External links

  • Ishibashi T, Yokoi N, Kinoshita S (2003). "Comparison of the effects of topical levobunolol and timolol solution on the human ocular surface". Cornea. 22 (8): 709–15. doi:10.1097/00003226-200311000-00001. PMID 14576520.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  • Ogasawara H, Yoshida A, Fujio N, Konno S, Ishiko S (1999). "". Nippon Ganka Gakkai Zasshi. 103 (7): 544–50. PMID 10443129.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  • Leung M, Grunwald J (1997). "Short-term effects of topical levobunolol on the human retinal circulation". Eye. 11 ( Pt 3): 371–6. PMID 9373479.
Drugs used for glaucoma preparations and miosis (S01E)
Sympathomimetics
Parasympathomimetics
muscarinic
muscarinic/nicotinic
acetylcholinesterase inhibitors
Carbonic anhydrase inhibitors/
(sulfonamides)
Beta blocking agents
Prostaglandin analogues (F)
Other agents
Adrenergic receptor modulators
α1
Agonists
Antagonists
α2
Agonists
Antagonists
β
Agonists
Antagonists
Categories: