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Befloxatone

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Befloxatone
Names
Preferred IUPAC name (5R)-5-(Methoxymethyl)-3-{4-phenyl}-1,3-oxazolidin-2-one
Identifiers
CAS Number
3D model (JSmol)
ChEMBL
ChemSpider
IUPHAR/BPS
KEGG
PubChem CID
UNII
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C15H18F3NO5/c1-22-9-12-8-19(14(21)24-12)10-2-4-11(5-3-10)23-7-6-13(20)15(16,17)18/h2-5,12-13,20H,6-9H2,1H3/t12-,13-/m1/s1Key: IALVDLPLCLFBCF-CHWSQXEVSA-N
  • InChI=1/C15H18F3NO5/c1-22-9-12-8-19(14(21)24-12)10-2-4-11(5-3-10)23-7-6-13(20)15(16,17)18/h2-5,12-13,20H,6-9H2,1H3/t12-,13-/m1/s1Key: IALVDLPLCLFBCF-CHWSQXEVBB
SMILES
  • O=C2O(CN2c1ccc(OCC(O)C(F)(F)F)cc1)COC
Properties
Chemical formula C15H18F3NO5
Molar mass 349.30233
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). ☒N verify (what is  ?) Infobox references
Chemical compound

Befloxatone (MD-370,503) is a reversible inhibitor of monoamine oxidase A.

References

  1. Emilien, G (March 1999). "Befloxatone (Synthelabo)". IDrugs. 2 (3): 247–253. PMID 16160936.
  2. Warot, Dominique; Berlin, Ivan; Patat, Alain; Durrieu, Geneviève; Zieleniuk, Isabelle; Puech, Alain J (October 1996). "Effects of Befloxatone, a Reversible Selective Monoamine Oxidase-A Inhibitor, on Psychomotor Function and Memory in Healthy Subjects". The Journal of Clinical Pharmacology. 1552-4604. 36 (10): 942–950. doi:10.1002/j.1552-4604.1996.tb04762.x. PMID 8930782. S2CID 36177710.


Monoamine metabolism modulators
Non-specific
AAADTooltip Aromatic L-amino acid decarboxylase
MAOTooltip Monoamine oxidase
Phenethylamines
(dopamine, epinephrine,
norepinephrine)
PAHTooltip Phenylalanine hydroxylase
THTooltip Tyrosine hydroxylase
DBHTooltip Dopamine beta-hydroxylase
PNMTTooltip Phenylethanolamine N-methyltransferase
COMTTooltip Catechol-O-methyl transferase
Tryptamines
(serotonin, melatonin)
TPHTooltip Tryptophan hydroxylase
AANATTooltip Serotonin N-acetyl transferase
ASMTTooltip Acetylserotonin O-methyltransferase
Histamine
HDCTooltip Histidine decarboxylase
HNMTTooltip Histamine N-methyltransferase
DAOTooltip Diamine oxidase
See also: Receptor/signaling modulators • Adrenergics • Dopaminergics • Melatonergics • Serotonergics • Monoamine reuptake inhibitors • Monoamine releasing agents • Monoamine neurotoxins
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