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DMeOB

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Chemical compound Pharmaceutical compound
DMeOB
Space-filling model of the DMeOB
Identifiers
IUPAC name
  • 1-(3-methoxyphenyl)-N-methanimine
CAS Number
PubChem CID
ChemSpider
CompTox Dashboard (EPA)
ECHA InfoCard100.164.778 Edit this at Wikidata
Chemical and physical data
FormulaC16H16N2O2
Molar mass268.316 g·mol
3D model (JSmol)
SMILES
  • COc2cc(ccc2)C=NN=Cc1cccc(OC)c1
InChI
  • InChI=1S/C16H16N2O2/c1-19-15-7-3-5-13(9-15)11-17-18-12-14-6-4-8-16(10-14)20-2/h3-12H,1-2H3/b17-11+,18-12+
  • Key:FBNPHFBYHYNMHC-JYFOCSDGSA-N
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DMeOB is a drug used in scientific research which acts as a negative allosteric modulator of the metabotropic glutamate receptor subtype mGluR5.

References

  1. O'Brien JA, Lemaire W, Chen TB, Chang RS, Jacobson MA, Ha SN, Lindsley CW, Schaffhauser HJ, Sur C, Pettibone DJ, Conn PJ, Williams DL (September 2003). "A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5". Molecular Pharmacology. 64 (3): 731–40. doi:10.1124/mol.64.3.731. PMID 12920211.
Metabotropic glutamate receptor modulators
Group I
mGluR1Tooltip Metabotropic glutamate receptor 1
mGluR5Tooltip Metabotropic glutamate receptor 5
Group II
mGluR2Tooltip Metabotropic glutamate receptor 2
mGluR3Tooltip Metabotropic glutamate receptor 3
Group III
mGluR4Tooltip Metabotropic glutamate receptor 4
mGluR6Tooltip Metabotropic glutamate receptor 6
mGluR7Tooltip Metabotropic glutamate receptor 7
mGluR8Tooltip Metabotropic glutamate receptor 8
See also: Receptor/signaling modulators • Ionotropic glutamate receptor modulators • Glutamate metabolism/transport modulators


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