Magnesium pyridoxal 5-phosphate glutamate

Chemical compound Pharmaceutical compound

Magnesium pyridoxal 5-phosphate glutamate
Clinical data

Trade names	Sedalipid
ATC code	C10AX07 (WHO)
Identifiers
IUPAC name (2S)-2,5-diamino-5-oxopentanoic acid; (4-formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate
CAS Number	62055-05-4 (magnesium salt)
PubChem CID	173846
ChemSpider	151728
CompTox Dashboard (EPA)	DTXSID00977622
Chemical and physical data
Formula	C₁₃H₂₀N₃O₉P
Molar mass	393.289 g·mol
3D model (JSmol)	Interactive image
SMILES O=C(N)CC(N)C(=O)O.O=P(O)(O)OCc1cnc(c(O)c1C=O)C
InChI InChI=1S/C8H10NO6P.C5H10N2O3/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14;6-3(5(9)10)1-2-4(7)8/h2-3,11H,4H2,1H3,(H2,12,13,14);3H,1-2,6H2,(H2,7,8)(H,9,10)/t;3-/m.0/s1 Key:BCARVEADLDZBJT-HVDRVSQOSA-N
(verify)

Magnesium pyridoxal 5-phosphate glutamate (trade name Sedalipid) is a hypolipidemic agent.

References

Schuitemaker GE, van der Pol GA, Aretz CP, Dinant GJ (2001). "A placebo-controlled, double-blind, randomised trial of magnesium-pyridoxal-5'-phosphate-glutamate for hypercholesterolaemia and other clinical-chemical risk factors of cardiovascular disease in a primary care setting". Eur. J. Clin. Pharmacol. 56 (12): 857–63. doi:10.1007/s002280000247. PMID 11317472.

Cholesterol absorption inhibitors, NPC1L1	Ezetimibe Hyzetimibe SCH-48461
Bile acid sequestrants/resins (LDL)	Colesevelam Colestilan Colestipol Colestyramine Colextran Soluble fiber such as psyllium and glucomannan

Statins (HMG-CoA reductase, LDL)	Atorvastatin Cerivastatin Fluvastatin Lovastatin Mevastatin Pitavastatin Pravastatin Rosuvastatin Simvastatin
Niacin and derivatives (HDL and LDL)	Acipimox Aluminium nicotinate Niacin Niceritrol Nicofuranose Nicotinyl alcohol
MTTP inhibitors (VLDL)	Dirlotapide Lomitapide Mitratapide
ATP citrate lyase inhibitors (LDL)	Bempedoic acid
Thyromimetics (VLDL)	Dextrothyroxine Resmetirom

Fibrates	Aluminium clofibrate Bezafibrate Choline fenofibrate Ciprofibrate Clinofibrate Clofibrate Clofibride Etofibrate Fenofibrate Gemfibrozil Nafenopin Pemafibrate Ronifibrate Simfibrate
Others	GW501516

ANGPTL3 inhibitors (LDL/HDL)

Combinations

Other

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