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Meglutol

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Chemical compound Not to be confused with Miglitol. Pharmaceutical compound
Meglutol
Clinical data
ATC code
Identifiers
IUPAC name
  • 3-hydroxy-3-methylpentanedioic acid
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.007.247 Edit this at Wikidata
Chemical and physical data
FormulaC6H10O5
Molar mass162.141 g·mol
3D model (JSmol)
SMILES
  • O=C(O)CC(O)(C)CC(=O)O
InChI
  • InChI=1S/C6H10O5/c1-6(11,2-4(7)8)3-5(9)10/h11H,2-3H2,1H3,(H,7,8)(H,9,10)
  • Key:NPOAOTPXWNWTSH-UHFFFAOYSA-N
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Meglutol (INN, also known as 3-hydroxy-3-methylglutaric acid, β-hydroxy-β-methylglutaric acid, and dicrotalic acid) is a hypolipidemic agent.

It occurs free in Crotalaria dura and C. globifera and is bound in dicrotaline (pyrrolizidine alkaloid).

See also

Lipid-lowering agents (C10)
GI tract
Cholesterol absorption inhibitors, NPC1L1
Bile acid sequestrants/resins (LDL)
Liver
Statins (HMG-CoA reductase, LDL)
Niacin and derivatives (HDL and LDL)
MTTP inhibitors (VLDL)
ATP citrate lyase inhibitors (LDL)
Thyromimetics (VLDL)
Blood vessels
PPAR agonists (LDL)
Fibrates
Others
CETP inhibitors (HDL)
PCSK9 inhibitors (LDL)
ANGPTL3 inhibitors (LDL/HDL)
Combinations
Other
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