A vesicular transport protein, or vesicular transporter, is a membrane protein that regulates or facilitates the movement of specific molecules across a vesicle's membrane. As a result, vesicular transporters govern the concentration of molecules within a vesicle.
Types
Examples include:
- Archain
- ARFs
- Clathrin
- Caveolin
- Dynamin and related proteins, such as the EHD protein family
- Rab proteins
- SNAREs
- Vesicular transport adaptor proteins e.g. Sorting nexins
- Synaptotagmin
- TRAPP complex
- Synaptophysin
- Auxilin
Pathways
There are multiple pathways, each using its own coat and GTPase.
- COP 1 (Cytosolic coat protein complex ) : retrograde transport; Golgi ----> Endoplasmic reticulum
- COP 2 (Cytosolic coat protein complex ) : anterograde transport; RER -----> cis-Golgi
- Clathrin : trans-Golgi ----> Lysosomes, Plasma membrane ----> Endosomes (receptor-mediated endocytosis)
See also
- Membrane transport protein
- Misplaced Pages:MeSH D12.776#MeSH D12.776.543.990 --- vesicular transport proteins
References
- Vesicular+Transport+Proteins at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
- Yasushi Sako (1 October 2010). Cell Signaling Reactions: Single-Molecular Kinetic Analysis. Springer. pp. 168–. ISBN 978-90-481-9863-4. Retrieved 15 December 2010.
| Membrane protein: vesicular transport proteins (TC 1F) | |||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Synaptic vesicle |
| ||||||||||||||||||||||||||
| COPI | |||||||||||||||||||||||||||
| COPII | |||||||||||||||||||||||||||
| RME/Clathrin | |||||||||||||||||||||||||||
| Caveolae | |||||||||||||||||||||||||||
| Other/ungrouped |
| ||||||||||||||||||||||||||
| See also vesicular transport protein disorders | |||||||||||||||||||||||||||
 | This membrane protein–related article is a stub. You can help Misplaced Pages by expanding it. |