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Desoxy-D2PM has two ]s which are used industrially in their purified form for resolution of chiral reagents during chemical synthesis.<ref>Bertelsen S, Halland N, Bachmann S, Marigo M, Braunton A, Jørgensen KA. Organocatalytic asymmetric α-bromination of aldehydes and ketones. ''Chem. Commun.'' 2005, 4821-4823{{doi|10.1039/b509366j}}</ref> Desoxy-D2PM has two ]s which are used industrially in their purified form for resolution of chiral reagents during chemical synthesis.<ref>Bertelsen S, Halland N, Bachmann S, Marigo M, Braunton A, Jørgensen KA. Organocatalytic asymmetric α-bromination of aldehydes and ketones. ''Chem. Commun.'' 2005, 4821-4823{{doi|10.1039/b509366j}}</ref>

As of the 4th November 2010, the ] ] announced a ban on the importation of 2-DPMP, following a recommendation from the ].<ref>, UK Home Office</ref> It will become a class B drug<ref name='draft legislation'> {{cite web | url = http://www.legislation.gov.uk/ukdsi/2012/9780111520857/memorandum/contents | title = The Misuse of Drugs Act 1971 (Amendment) Order 2012 | accessdate = 2012-03-11 | date = 2012-01-27 | format = PDF | publisher = UK Home Office}}</ref> on the 28th March.<ref name='ACMD's comments'> {{cite web | url = http://www.homeoffice.gov.uk/publications/alcohol-drugs/drugs/2-dpmp-compounds/D2PM?view=Binary | title = The Misuse of Drugs Act 1971 (Amendment) Order 2012 | accessdate = 2012-03-11 | date = 2012-01-27 | format = PDF | publisher = UK Home Office}}</ref>


== References == == References ==

Revision as of 09:31, 11 March 2012

Pharmaceutical compound
2-Diphenylmethylpyrrolidine
Identifiers
IUPAC name
  • (RS)-2-(Diphenylmethyl)pyrrolidine
CAS Number
PubChem CID
ChemSpider
CompTox Dashboard (EPA)
ECHA InfoCard100.162.251 Edit this at Wikidata
Chemical and physical data
FormulaC17H19N
Molar mass237.339 g·mol
3D model (JSmol)
SMILES
  • c1cc(ccc1)C(c2ccccc2)C3NCCC3
InChI
  • InChI=1S/C17H19N/c1-3-8-14(9-4-1)17(16-12-7-13-18-16)15-10-5-2-6-11-15/h1-6,8-11,16-18H,7,12-13H2
  • Key:OXOBKZZXZVFOBB-UHFFFAOYSA-N
  (verify)

2-Diphenylmethylpyrrolidine (Desoxy-D2PM), also known as 2-benzhydrylpyrrolidine, is a stimulant psychoactive drug. It is the 4-dehydroxylated structural analogue of diphenylprolinol (D2PM), and is also similar in structure to desoxypipradrol (2-DPMP), both of which act as norepinephrine-dopamine reuptake inhibitors (NDRIs). Like D2PM and 2-DPMP, Desoxy-D2PM is sold as a designer drug, and has been used in the manufacture of legal highs. It has been marketed under the names A3A New Generation, A3A Methano, and Green Powder, and has been reported to cause hallucinations, violent behavior, dilated pupils, tachycardia, and high blood pressure.

Desoxy-D2PM has two enantiomers which are used industrially in their purified form for resolution of chiral reagents during chemical synthesis.

As of the 4th November 2010, the UK Home Office announced a ban on the importation of 2-DPMP, following a recommendation from the ACMD. It will become a class B drug on the 28th March.Cite error: The <ref> tag has too many names (see the help page).

References

  1. http://www.ncbi.nlm.nih.gov/pubmed/22055832
  2. http://www.droganews.it/pubdownload.php?id=2472
  3. http://ewsd.wiv-isp.be/Other%20information%20on%20new%20psychoactive%20substances/Desoxy-D2PM/Report_UK_Dec%202010_Green%20Powder%20called%20A3A%20Methano.pdf
  4. Bertelsen S, Halland N, Bachmann S, Marigo M, Braunton A, Jørgensen KA. Organocatalytic asymmetric α-bromination of aldehydes and ketones. Chem. Commun. 2005, 4821-4823doi:10.1039/b509366j
  5. Import ban on psychoactive drug, UK Home Office
  6. "The Misuse of Drugs Act 1971 (Amendment) Order 2012" (PDF). UK Home Office. 2012-01-27. Retrieved 2012-03-11.
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ATC code: N06B


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