Nicofuranose - Misplaced Pages

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Nicofuranose
Clinical data

ATC code	C10AD03 (WHO)
Identifiers
IUPAC name 1,3,4,6-tetrakis-O-(pyridin-3-ylcarbonyl)-β-D-fructofuranose
CAS Number	15351-13-0
PubChem CID	25495
ChemSpider	23791
UNII	GF99P6327K
KEGG	D07189
CompTox Dashboard (EPA)	DTXSID6023365
ECHA InfoCard	100.035.789
Chemical and physical data
Formula	C₃₀H₂₄N₄O₁₀
Molar mass	600.540 g·mol
3D model (JSmol)	Interactive image
SMILES C1=CC(=CN=C1)C(=O)OC2(((O2)(COC(=O)C3=CN=CC=C3)O)OC(=O)C4=CN=CC=C4)OC(=O)C5=CN=CC=C5
InChI InChI=1S/C30H24N4O10/c35-26(19-5-1-9-31-13-19)40-17-23-24(42-28(37)21-7-3-11-33-15-21)25(43-29(38)22-8-4-12-34-16-22)30(39,44-23)18-41-27(36)20-6-2-10-32-14-20/h1-16,23-25,39H,17-18H2/t23-,24-,25+,30-/m1/s1 Key:FUWFSXZKBMCSKF-ZASNTINBSA-N
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Nicofuranose is a niacin derivative used as a hypolipidemic agent.

References

Kopelevich VM, Gunar VI (1999). "Some approaches to the directed search for new drugs based on nicotinic acid". Pharm Chem J. 33 (4): 177–187. doi:10.1007/BF02509934.

Cholesterol absorption inhibitors, NPC1L1	Ezetimibe Hyzetimibe SCH-48461
Bile acid sequestrants/resins (LDL)	Colesevelam Colestilan Colestipol Colestyramine Colextran Soluble fiber such as psyllium and glucomannan

Statins (HMG-CoA reductase, LDL)	Atorvastatin Cerivastatin Fluvastatin Lovastatin Mevastatin Pitavastatin Pravastatin Rosuvastatin Simvastatin
Niacin and derivatives (HDL and LDL)	Acipimox Aluminium nicotinate Niacin Niceritrol Nicofuranose Nicotinyl alcohol
MTTP inhibitors (VLDL)	Dirlotapide Lomitapide Mitratapide
ATP citrate lyase inhibitors (LDL)	Bempedoic acid
Thyromimetics (VLDL)	Dextrothyroxine Resmetirom

Fibrates	Aluminium clofibrate Bezafibrate Choline fenofibrate Ciprofibrate Clinofibrate Clofibrate Clofibride Etofibrate Fenofibrate Gemfibrozil Nafenopin Pemafibrate Ronifibrate Simfibrate
Others	GW501516

ANGPTL3 inhibitors (LDL/HDL)

Combinations

Other

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