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Terbequinil

Clinical data
ATC code	none
Identifiers
IUPAC name 1-(methoxymethyl)-4-oxo-N-propylquinoline-3-carboxamide
CAS Number	113079-82-6
PubChem CID	65916
ChemSpider	59325
UNII	0DH9WUS03O
CompTox Dashboard (EPA)	DTXSID50150281
Chemical and physical data
Formula	C15H18N2O3
Molar mass	274.320 g·mol
3D model (JSmol)	Interactive image
SMILES CCCNC(=O)C1=CN(C2=CC=CC=C2C1=O)COC
InChI InChI=1S/C15H18N2O3/c1-3-8-16-15(19)12-9-17(10-20-2)13-7-5-4-6-11(13)14(12)18/h4-7,9H,3,8,10H2,1-2H3,(H,16,19) Key:RIPDGZHPNKQLDC-UHFFFAOYSA-N
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Terbequinil (SR-25776) is a stimulant and nootropic drug which acts as a partial inverse agonist at benzodiazepine sites on the GABA_A receptor. In human trials it was found to partially reverse the sedative and amnestic effects of the hypnotic drug triazolam with only slight effects when administered by itself.

See also

• GABA_A receptor negative allosteric modulator
• GABA_A receptor § Ligands

References

1. Warot D, Danjou P, Douillet P, Keane P, Puech AJ (1994). "Cognitive impairments induced by triazolam in healthy volunteers: antagonism by a partial inverse agonist of benzodiazepine receptor". Therapie. 49 (1): 23–6. PMID 8091361.

• Drugs not assigned an ATC code
• 2-Quinolones
• Ethers
• Carboxamides
• GABAA receptor negative allosteric modulators