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Latest revision as of 11:21, 23 January 2023 edit undoEntranced98 (talk | contribs)Extended confirmed users, Pending changes reviewers, Rollbackers173,284 edits Importing Wikidata short description: "Chemical compound"Tag: Shortdesc helper |
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{{Short description|Chemical compound}} |
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{{drugbox |
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{{Missing information|everything|date=January 2017}} |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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{{Drugbox |
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| UNII = 0S9SLS3L93 |
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| verifiedrevid = 437132997 |
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| verifiedrevid = 447821444 |
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| IUPAC_name = 3-(dimethylcarbamoyl)propyl 2-(4-chlorophenoxy)-2-methylpropanoate |
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| IUPAC_name = 3-(dimethylcarbamoyl)propyl 2-(4-chlorophenoxy)-2-methylpropanoate |
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| image = Clofibride.svg |
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| image = Clofibride.svg |
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<!--Clinical data--> |
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| tradename = |
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| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --> |
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| pregnancy_US = <!-- A / B / C / D / X --> |
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| pregnancy_category = |
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| legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 --> |
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| legal_CA = <!-- / Schedule I, II, III, IV, V, VI, VII, VIII --> |
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| legal_UK = <!-- GSL / P / POM / CD / Class A, B, C --> |
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| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V --> |
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| legal_status = |
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| routes_of_administration = |
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<!--Pharmacokinetic data--> |
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| bioavailability = |
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| protein_bound = |
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| metabolism = ] to ]; ] ] |
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| elimination_half-life = 12 hours (clofibric acid) |
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| excretion = ] (mostly) and fecal |
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<!--Identifiers--> |
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| CAS_number = 26717-47-5 |
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| ATC_prefix = C10 |
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| ATC_suffix = AB10 |
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| PubChem = 160134 |
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| ChEMBL = 1697831 |
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| DrugBank_Ref = {{drugbankcite|correct|drugbank}} |
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| DrugBank = |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID = 140758 |
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| ChemSpiderID = 140758 |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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| InChI = 1/C16H22ClNO4/c1-16(2,22-13-9-7-12(17)8-10-13)15(20)21-11-5-6-14(19)18(3)4/h7-10H,5-6,11H2,1-4H3 |
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| UNII = 0S9SLS3L93 |
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| KEGG_Ref = {{keggcite|correct|kegg}} |
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| KEGG = D07188 |
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<!--Chemical data--> |
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| C=16 | H=22 | Cl=1 | N=1 | O=4 |
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| smiles = Clc1ccc(OC(C(=O)OCCCC(=O)N(C)C)(C)C)cc1 |
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| smiles = Clc1ccc(OC(C(=O)OCCCC(=O)N(C)C)(C)C)cc1 |
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| InChIKey = CXQGFLBVUNUQIA-UHFFFAOYAF |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChI = 1S/C16H22ClNO4/c1-16(2,22-13-9-7-12(17)8-10-13)15(20)21-11-5-6-14(19)18(3)4/h7-10H,5-6,11H2,1-4H3 |
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| StdInChI = 1S/C16H22ClNO4/c1-16(2,22-13-9-7-12(17)8-10-13)15(20)21-11-5-6-14(19)18(3)4/h7-10H,5-6,11H2,1-4H3 |
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey = CXQGFLBVUNUQIA-UHFFFAOYSA-N |
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| StdInChIKey = CXQGFLBVUNUQIA-UHFFFAOYSA-N |
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| CAS_number = 26717-47-5 |
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| ATC_prefix = C10 |
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| ATC_suffix = AB10 |
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| PubChem = 160134 |
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| DrugBank_Ref = {{drugbankcite|correct|drugbank}} |
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| DrugBank = |
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| KEGG_Ref = {{keggcite|correct|kegg}} |
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| KEGG = D07188 |
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| C=16|H=22|Cl=1|N=1|O=4 |
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| molecular_weight = 327.803 g/mol |
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| bioavailability = |
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| protein_bound = |
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| metabolism = ] to clofibric acid; ] ] |
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| elimination_half-life = 12 hours (clofibric acid) |
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| excretion = ] (mostly) and fecal |
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| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --> |
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| pregnancy_US = <!-- A / B / C / D / X --> |
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| pregnancy_category= |
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| legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 --> |
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| legal_CA = <!-- / Schedule I, II, III, IV, V, VI, VII, VIII --> |
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| legal_UK = <!-- GSL / P / POM / CD / Class A, B, C --> |
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| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V --> |
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| legal_status = |
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| routes_of_administration = |
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}} |
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}} |
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'''Clofibride''' is a ]. |
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'''Clofibride''' is a ]. Clofibride is a derivative of ]. In the body it is converted into 4-chlorophenoxyisobutyric acid (]),<ref>{{Cite web|url=https://pubchem.ncbi.nlm.nih.gov/compound/160134|title=Clofibride}}</ref> which is the true ].<ref name="römpp">{{RömppOnline|Name=Clofibrat |Datum=06. Mai 2020 |ID=RD-03-02073 }}</ref> So clofibride, just like clofibrate is a ] of clofibric acid. |
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==References== |
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{{Reflist|2}} |
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{{Lipid modifying agents}} |
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{{Lipid modifying agents}} |
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{{PPAR modulators}} |
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] |
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] |
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{{cardiovascular-drug-stub}} |
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{{cardiovascular-drug-stub}} |
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] |
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