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Lamivudine/raltegravir

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Combination drug for HIV

Pharmaceutical compound
Lamivudine/raltegravir
Combination of
LamivudineReverse-transcriptase inhibitor
RaltegravirIntegrase inhibitor
Clinical data
Trade namesDutrebis
Routes of
administration
Oral
ATC code
Legal status
Legal status
Identifiers
CAS Number
KEGG

Lamivudine/raltegravir, sold under the brand name Dutrebis, is a fixed-dose combination antiretroviral medication used in the treatment of HIV/AIDS. It contains lamivudine and raltegravir. It is taken by mouth. Side effects may include lactic acidosis, pancreatitis, liver failure, and severe skin rashes. It was approved for medical use in the United States in 2015.

Lamivudine/raltegravir is not available in the United States.

References

  1. ^ "Dutrebis (lamivudine and raltegravir)" (PDF). U.S. Food and Drug Administration (FDA). Retrieved 10 December 2017.
  2. "Dutrebis (lamivudine and raltegravir) tablet". U.S. Food and Drug Administration (FDA). 11 April 2016. Retrieved 24 January 2020.
  3. "Dutrebis (lamivudine and raltegravir) FDA Approval History". Drugs.com. 6 February 2015. Retrieved 24 January 2020.

External links

Antiviral drugs: antiretroviral drugs used against HIV (primarily J05)
Capsid inhibitors
Entry/fusion inhibitors
(Discovery and development)
Integrase inhibitors
(Integrase strand transfer inhibitors (INSTI))
Maturation inhibitors
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(Discovery and development)
1 generation
2 generation
Reverse-transcriptase
inhibitors
(RTIs)
Nucleoside and
nucleotide (NRTI)
Non-nucleoside (NNRTI)
(Discovery and development)
1 generation
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Combined formulations
Pharmacokinetic boosters
Experimental agents
Uncoating inhibitors
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Failed agents
°DHHS recommended initial regimen options. Formerly or rarely used agent.
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