Misplaced Pages

OR2Z1
Identifiers
Aliases	OR2Z1, OR19-4, OR2Z2, olfactory receptor family 2 subfamily Z member 1
External IDs	MGI: 3030206; HomoloGene: 17287; GeneCards: OR2Z1; OMA:OR2Z1 - orthologs
Gene location (Human) Chr. Chromosome 19 (human) Band 19p13.2 Start 8,721,634 bp End 8,732,160 bp
Gene location (Mouse) Chr. Chromosome 8 (mouse) Band 8|8 B3.3 Start 72,795,062 bp End 72,814,474 bp
RNA expression pattern Bgee Human Mouse (ortholog) n/a Top expressed in granulocyte BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 284383 404315 Ensembl ENSG00000181733 ENSMUSG00000069998 UniProt Q8NG97 Q7TRY2 RefSeq (mRNA) NM_001004699 NM_207555 RefSeq (protein) NP_001004699 NP_997438 Location (UCSC) Chr 19: 8.72 – 8.73 Mb Chr 8: 72.8 – 72.81 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 2Z1 is a protein that in humans is encoded by the OR2Z1 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

References

1. ^ GRCh38: Ensembl release 89: ENSG00000181733 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000069998 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. ^ "Entrez Gene: OR2Z1 olfactory receptor, family 2, subfamily Z, member 1".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR2Z1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This transmembrane receptor-related article is a stub. You can help Misplaced Pages by expanding it.

• v
• t
• e

• Genes on human chromosome 19
• Transmembrane receptor stubs
• Olfactory receptors