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OR4N2
Identifiers
Aliases	OR4N2, OR14-13, OR14-8, olfactory receptor family 4 subfamily N member 2
External IDs	MGI: 3030567; HomoloGene: 128266; GeneCards: OR4N2; OMA:OR4N2 - orthologs
Gene location (Human) Chr. Chromosome 14 (human) Band 14q11.2 Start 19,719,015 bp End 19,830,253 bp
Gene location (Mouse) Chr. Chromosome 14 (mouse) Band 14|14 C1 Start 50,533,348 bp End 50,538,979 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle gonad left testis right testis islet of Langerhans prefrontal cortex Brodmann area 9 respiratory system subdivision of respiratory system lung Top expressed in embryo testicle spermatid More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity transmembrane signaling receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell detection of chemical stimulus involved in sensory perception signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 390429 258657 Ensembl ENSG00000176294 ENSMUSG00000090874 UniProt Q8NGD1 Q14AK5 RefSeq (mRNA) NM_001004723 NM_146663 RefSeq (protein) NP_001004723 NP_666874 Location (UCSC) Chr 14: 19.72 – 19.83 Mb Chr 14: 50.53 – 50.54 Mb PubMed search
Wikidata
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Olfactory receptor 4N2 is a protein that in humans is encoded by the OR4N2 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

References

1. ^ GRCh38: Ensembl release 89: ENSG00000176294 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000090874 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. ^ "Entrez Gene: OR4N2 olfactory receptor, family 4, subfamily N, member 2".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR4N2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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• Olfactory receptors