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OR52B6
Identifiers
Aliases	OR52B6, OR11-47, olfactory receptor family 52 subfamily B member 6
External IDs	MGI: 3030452; HomoloGene: 72966; GeneCards: OR52B6; OMA:OR52B6 - orthologs
Gene location (Human) Chr. Chromosome 11 (human) Band 11p15.4 Start 5,580,877 bp End 5,581,884 bp
Gene location (Mouse) Chr. Chromosome 7 (mouse) Band 7|7 E3 Start 103,239,310 bp End 103,249,655 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sural nerve Achilles tendon stromal cell of endometrium left ovary muscle of thigh myometrium right ovary Top expressed in testicle More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 340980 259049 Ensembl ENSG00000187747 ENSMUSG00000073945 UniProt Q8NGF0 K7N6B3 RefSeq (mRNA) NM_001005162 NM_147047 RefSeq (protein) NP_001005162 NP_667258 Location (UCSC) Chr 11: 5.58 – 5.58 Mb Chr 7: 103.24 – 103.25 Mb PubMed search
Wikidata
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Olfactory receptor 52B6 is a protein that in humans is encoded by the OR52B6 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

References

1. ^ GRCh38: Ensembl release 89: ENSG00000187747 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000073945 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. ^ "Entrez Gene: OR52B6 olfactory receptor, family 52, subfamily B, member 6".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–2589. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR52B6+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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