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OR52E6
Identifiers
Aliases	OR52E6, OR11-58, olfactory receptor family 52 subfamily E member 6
External IDs	HomoloGene: 133880; GeneCards: OR52E6; OMA:OR52E6 - orthologs
Gene location (Human) Chr. Chromosome 11 (human) Band 11p15.4 Start 5,840,928 bp End 5,841,952 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in epithelium of colon placenta fundus n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 390078 n/a Ensembl ENSG00000205409 n/a UniProt Q96RD3 n/a RefSeq (mRNA) NM_001005167 n/a RefSeq (protein) NP_001005167 n/a Location (UCSC) Chr 11: 5.84 – 5.84 Mb n/a PubMed search n/a
Wikidata
View/Edit Human

Olfactory receptor 52E6 is a protein that in humans is encoded by the OR52E6 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

References

1. ^ GRCh38: Ensembl release 89: ENSG00000205409 – Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. ^ "Entrez Gene: OR52E6 olfactory receptor, family 52, subfamily E, member 6".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR52E6+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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