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OR52B2
Identifiers
Aliases	OR52B2, OR11-70, olfactory receptor family 52 subfamily B member 2
External IDs	MGI: 3030525; HomoloGene: 17483; GeneCards: OR52B2; OMA:OR52B2 - orthologs
Gene location (Human) Chr. Chromosome 11 (human) Band 11p15.4 Start 6,169,355 bp End 6,170,326 bp
Gene location (Mouse) Chr. Chromosome 7 (mouse) Band 7|7 E3 Start 104,984,716 bp End 104,991,477 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gonad ganglionic eminence Top expressed in respiratory epithelium nasal epithelium olfactory epithelium embryo superior frontal gyrus striatum of neuraxis Hypothalamus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 255725 259063 Ensembl ENSG00000255307 ENSMUSG00000043948 UniProt Q96RD2 Q8VGW5 RefSeq (mRNA) NM_001004052 NM_147061 RefSeq (protein) NP_001004052 NP_667272 Location (UCSC) Chr 11: 6.17 – 6.17 Mb Chr 7: 104.98 – 104.99 Mb PubMed search
Wikidata
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Olfactory receptor 52B2 is a protein that in humans is encoded by the OR52B2 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

References

1. ^ GRCh38: Ensembl release 89: ENSG00000255307 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000043948 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. ^ "Entrez Gene: OR52B2 olfactory receptor, family 52, subfamily B, member 2".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. CiteSeerX 10.1.1.135.3652. doi:10.1006/geno.2002.6830. PMID 12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR52B2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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