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OR6S1
Identifiers
Aliases	OR6S1, OR14-37, OR6S1Q, olfactory receptor family 6 subfamily S member 1
External IDs	MGI: 3030584; HomoloGene: 19719; GeneCards: OR6S1; OMA:OR6S1 - orthologs
Gene location (Human) Chr. Chromosome 14 (human) Band 14q11.2 Start 20,640,696 bp End 20,641,691 bp
Gene location (Mouse) Chr. Chromosome 14 (mouse) Band 14|14 C1 Start 51,303,758 bp End 51,311,892 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in lymph node urinary bladder Top expressed in lung More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 341799 404319 Ensembl ENSG00000181803 ENSMUSG00000035932 UniProt Q8NH40 E9Q0Z1 RefSeq (mRNA) NM_001001968 NM_207558 RefSeq (protein) NP_001001968 NP_997441 Location (UCSC) Chr 14: 20.64 – 20.64 Mb Chr 14: 51.3 – 51.31 Mb PubMed search
Wikidata
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Olfactory receptor 6S1 is a protein that in humans is encoded by the OR6S1 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

References

1. ^ GRCh38: Ensembl release 89: ENSG00000181803 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000035932 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. ^ "Entrez Gene: OR6S1 olfactory receptor, family 6, subfamily S, member 1".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR6S1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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