Cefpimizole: Difference between revisions

Revision as of 23:34, 30 June 2011 editCheMoBot (talk \| contribs)Bots141,565 edits Updating {{drugbox}} (changes to verified fields - updated 'ChemSpiderID_Ref', 'StdInChI_Ref', 'StdInChIKey_Ref', 'ChEMBL_Ref') per Chem/Drugbox validation (report [[Misplaced Pages talk:WikiProject_Ph← Previous edit		Revision as of 22:49, 13 August 2011 edit undoCheMoBot (talk \| contribs)Bots141,565 edits Updating {{drugbox}} (no changed fields - added verified revid - updated 'ChemSpiderID_Ref', 'DrugBank_Ref', 'ChEMBL_Ref', 'ChEBI_Ref', 'StdInChI_Ref', 'StdInChIKey_Ref', 'ChEBI_Ref') per [[Misplaced Pages:WikiProject Chemicals/Chembox validation\|Chem/DrugNext edit →
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	{{drugbox		{{drugbox
		⚫	\| UNII_Ref = {{fdacite\|correct\|FDA}}
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	\| UNII = 24S58UHU7N		\| UNII = 24S58UHU7N
	\| verifiedrevid = ~~402797569~~		\| verifiedrevid = 437136825
	\| IUPAC_name = 2--2-phenylacetyl]amino)-8-oxo-5-thia-1-azabicyclooct-2-en-3-yl]methyl)pyridin-1-ium-4-yl]ethanesulfonate		\| IUPAC_name = 2--2-phenylacetyl]amino)-8-oxo-5-thia-1-azabicyclooct-2-en-3-yl]methyl)pyridin-1-ium-4-yl]ethanesulfonate
	\| image = Cefpimizole.png		\| image = Cefpimizole.png
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	\| PubChem = 68597		\| PubChem = 68597
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	\| DrugBank =		\| DrugBank =
	\| KEGG_Ref = {{keggcite\|correct\|kegg}}		\| KEGG_Ref = {{keggcite\|correct\|kegg}}

Revision as of 22:49, 13 August 2011

Pharmaceutical compound

Cefpimizole
Clinical data

ATC code	none
Legal status
Legal status	In general: ℞ (Prescription only)
Identifiers
IUPAC name 2--2-phenylacetyl]amino)-8-oxo-5-thia-1-azabicyclooct-2-en-3-yl]methyl)pyridin-1-ium-4-yl]ethanesulfonate
CAS Number	84880-03-5
PubChem CID	68597
UNII	24S58UHU7N
KEGG	D03427
CompTox Dashboard (EPA)	DTXSID001024675 DTXSID70920069, DTXSID001024675
Chemical and physical data
Formula	C₂₈H₂₆N₆O₁₀S₂
Molar mass	670.67 g/mol g·mol
3D model (JSmol)	Interactive image
SMILES C1C(=C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)NC(=O)C4=C(NC=N4)C(=O)O)C(=O)O) C5=CC=C(C=C5)CCS(=O)(=O)
(verify)

Cefpimizole (INN) is a third-generation cephalosporin antibiotic.

Hara K, Shimada J (1987). "". Jpn J Antibiot (in Japanese). 40 (6): 1108–22. PMID 3312705. {{cite journal}}: Unknown parameter |month= ignored (help)

This systemic antibiotic-related article is a stub. You can help Misplaced Pages by expanding it.

β-lactams
(inhibit synthesis
of peptidoglycan
layer of bacterial
cell wall by binding
to and inhibiting
PBPs, a group of
D-alanyl-D-alanine
transpeptidases)

β-lactamase sensitive (1st generation)	Benzylpenicillin (G) Benzathine benzylpenicillin Procaine benzylpenicillin Phenoxymethylpenicillin (V) Propicillin Pheneticillin Azidocillin Clometocillin Penamecillin
β-lactamase resistant (2nd generation)	Cloxacillin (Dicloxacillin Flucloxacillin) Oxacillin Nafcillin Methicillin

Aminopenicillins (3rd generation)	Amoxicillin Ampicillin (Pivampicillin Hetacillin Bacampicillin Lenampicillin Metampicillin Talampicillin) Epicillin
Carboxypenicillins (4th generation)	Ticarcillin Carbenicillin / Carindacillin Temocillin
Ureidopenicillins (4th generation)	Piperacillin Azlocillin Mezlocillin
Other	Mecillinam (Pivmecillinam) Sulbenicillin

1st generation	Cefazolin Cefalexin Cefadroxil Cefapirin Cefazedone Cefazaflur Cefradine Cefroxadine Ceftezole Cefaloglycin Cefacetrile Cefalonium Cefaloridine Cefalotin Cefatrizine
2nd generation	Cefaclor Cefprozil Cefuroxime Cefuroxime axetil Cefamandole Cefonicid Ceforanide Cefuzonam Cephamycin (Cefoxitin Cefotetan Cefminox Cefbuperazone Cefmetazole) Carbacephem (Loracarbef)
3rd generation	Cefixime Ceftriaxone Cefotaxime Antipseudomonal (Ceftazidime Cefoperazone) Cefdinir Cefcapene Cefdaloxime Ceftizoxime Cefmenoxime Cefpiramide Cefpodoxime Ceftibuten Cefditoren Cefotiam Cefetamet Cefodizime Cefpimizole Cefsulodin Cefteram Ceftiolene Oxacephem (Flomoxef Latamoxef)
4th generation	Cefepime Cefozopran Cefpirome Cefquinome
5th generation	Ceftaroline fosamil Ceftolozane Ceftobiprole
Siderophore	Cefiderocol
Veterinary	Ceftiofur Cefquinome Cefovecin

Combinations

Lipopeptides	Insert into bacterial cell wall causing perforation and depolarization: Daptomycin Surfactin
Other	Inhibits PG elongation and crosslinking: Ramoplanin

Intracellular

Inhibit PG subunit synthesis and transport: NAM synthesis inhibition (Fosfomycin)
DADAL/AR inhibitors (Cycloserine)
bactoprenol inhibitors (Bacitracin)

Other