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Pivhydrazine

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(Redirected from Pivalylbenzhydrazine) Chemical compound Pharmaceutical compound
Pivhydrazine
Clinical data
Other namesAngorvid, Betamezid, Neomarsilid, Pivazide, Pivhydrazine
Routes of
administration		Oral
ATC code
  • none
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
IUPAC name
  • N'-benzyl-2,2-dimethyl-propanehydrazide
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.005.620 Edit this at Wikidata
Chemical and physical data
FormulaC12H18N2O
Molar mass206.289 g·mol
InChI
  • InChI=1S/C12H18N2O/c1-12(2,3)11(15)14-13-9-10-7-5-4-6-8-10/h4-8,13H,9H2,1-3H3,(H,14,15)
  • Key:FWWDFDMCZLOXQI-UHFFFAOYSA-N
  (verify)

Pivhydrazine (trade name Tersavid), also known as pivalylbenzhydrazine and pivazide, is an irreversible and non-selective monoamine oxidase inhibitor (MAOI) of the hydrazine family. It was formerly used as an antidepressant in the 1960s, but has since been discontinued.

See also

References

  1. Herman ZS, Sokola A, Lenartowicz H, Zieliński M, Depta L (May–June 1976). "The influence of antidepressive drugs on the level of acetylcholine and on the acetylcholinesterase activity in the brain of rats". Polish Journal of Pharmacology and Pharmacy. 28 (4): 313–21. OCLC 1586290. PMID 981020.
  2. Bolton GC, Griffiths LA (November–December 1979). "The metabolic disposition of [14C]pivhydrazine, [14C]mebanazine, and [14C]benzylhydrazine in the rat". Drug Metabolism and Disposition. 7 (6): 388–92. OCLC 1784380. PMID 43225.
  3. Mikhaĭlova TV, Gilev AP, Khavronina-Gureeva ZP (1969). "". Farmakologiia i Toksikologiia (in Russian). 32 (6): 652–6. OCLC 1568906. PMID 5381593.
Antidepressants (N06A)
Specific reuptake inhibitors and/or receptor modulators
SSRIsTooltip Selective serotonin reuptake inhibitors
SNRIsTooltip Serotonin–norepinephrine reuptake inhibitors
NRIsTooltip Norepinephrine reuptake inhibitors
NDRIsTooltip Norepinephrine–dopamine reuptake inhibitors
NaSSAsTooltip Noradrenergic and specific serotonergic antidepressants
SARIsTooltip Serotonin antagonist and reuptake inhibitors
SMSTooltip Serotonin modulator and stimulators
Others
Tricyclic and tetracyclic antidepressants
TCAsTooltip Tricyclic antidepressants
TeCAsTooltip Tetracyclic antidepressants
Others
Monoamine oxidase inhibitors
Non-selective
MAOATooltip Monoamine oxidase A-selective
MAOBTooltip Monoamine oxidase B-selective
Adjunctive therapies
Miscellaneous
Monoamine metabolism modulators
Non-specific
AAADTooltip Aromatic L-amino acid decarboxylase
MAOTooltip Monoamine oxidase
Phenethylamines
(dopamine, epinephrine,
norepinephrine)
PAHTooltip Phenylalanine hydroxylase
THTooltip Tyrosine hydroxylase
DBHTooltip Dopamine beta-hydroxylase
PNMTTooltip Phenylethanolamine N-methyltransferase
COMTTooltip Catechol-O-methyl transferase
Tryptamines
(serotonin, melatonin)
TPHTooltip Tryptophan hydroxylase
AANATTooltip Serotonin N-acetyl transferase
ASMTTooltip Acetylserotonin O-methyltransferase
Histamine
HDCTooltip Histidine decarboxylase
HNMTTooltip Histamine N-methyltransferase
DAOTooltip Diamine oxidase
See also: Receptor/signaling modulators • Adrenergics • Dopaminergics • Melatonergics • Serotonergics • Monoamine reuptake inhibitors • Monoamine releasing agents • Monoamine neurotoxins
Hydrazines
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