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Oxotremorine

File:Oxotremorine.png
Clinical data
ATC code	none
Identifiers
IUPAC name 1-(4-pyrrolidin- 1-ylbut- 2-yn- 1-yl) pyrrolidin- 2-one
CAS Number	70-22-4
IUPHAR/BPS	302
CompTox Dashboard (EPA)	DTXSID10220252
ECHA InfoCard	100.000.662
Chemical and physical data
Formula	C12H18N2O
Molar mass	206.28 g·mol
(verify)

Oxotremorine is a cholinomimetic that acts as a non-selective muscarinic acetylcholine receptor agonist.

Oxotremorine produces ataxia, tremor and spasticity, similar to those symptoms seen in Parkinsonism, and has thus become a research tool in experimental studies aimed at determining more effective anti-Parkinsonian drugs.

References

1. Tang C, Castoldi AF, Costa LG (1993). "Effects of the muscarinic agonist oxotremorine on membrane fluidity in rat lymphocytes". Biochem. Mol. Biol. Int. 29 (6): 1047–54. PMID 8330013. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
2. Craig, C. R., Stitzel, R. E., Modern Pharmacology. Little, Brown. Boston, 2006.

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