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2,5-Dimethoxy-4-(2-fluoroethyl)amphetamine

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2,5-Dimethoxy-4-(2-fluoroethyl)amphetamine
Names
Preferred IUPAC name 1-propan-2-amine
Identifiers
CAS Number
3D model (JSmol)
ChEMBL
ChemSpider
PubChem CID
UNII
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C13H20FNO2/c1-9(15)6-11-8-12(16-2)10(4-5-14)7-13(11)17-3/h7-9H,4-6,15H2,1-3H3Key: QLENKWFQUHHBKZ-UHFFFAOYSA-N
  • InChI=1/C13H20FNO2/c1-9(15)6-11-8-12(16-2)10(4-5-14)7-13(11)17-3/h7-9H,4-6,15H2,1-3H3Key: QLENKWFQUHHBKZ-UHFFFAOYAO
SMILES
  • C1(=CC(=C(C=C1CC(C)N)OC)CCF)OC
  • COc1cc(CC(C)N)c(cc1CCF)OC
Properties
Chemical formula C13H20FNO2
Molar mass 241.306 g·mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). ☒verify (what is  ?) Infobox references
Chemical compound

2,5-Dimethoxy-4-(2-fluoroethyl)amphetamine (DOEF; also known as dimethoxyfluoroethylamphetamine) is a lesser-known psychedelic drug and member of the DOx class. DOEF was first synthesized by Alexander Shulgin. In his book PiHKAL, the dosage range is listed as 2–3.5 mg, and the duration is listed as 12–16 hours. Very little data exists about the pharmacological properties, metabolism, and toxicity of DOEF.

See also

References

  1. Gerdes, John M.; Mathis, Chester A.; Shulgin, Alexander T. (1988). "Synthesis of 1-[2′,5′-dimethoxy-4′-(β-fluoroethyl)phenyl]-2-aminopropane:studies related to 18F-labeled serotonin receptor ligands". Tetrahedron Letters. 29 (50): 6537–6539. doi:10.1016/S0040-4039(00)82391-6.
  2. Trachsel, Daniel (2012). "Fluorine in psychedelic phenethylamines". Drug Testing and Analysis. 4 (7–8): 577–590. doi:10.1002/dta.413. PMID 22374819.
  3. DOEF Entry in PiHKAL
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