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Oxametacin

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Chemical compound Pharmaceutical compound
Oxametacin
Clinical data
ATC code
Identifiers
IUPAC name
  • 2--N-hydroxyacetamide
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.043.785 Edit this at Wikidata
Chemical and physical data
FormulaC19H17ClN2O4
Molar mass372.81 g·mol
3D model (JSmol)
SMILES
  • CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)NO
InChI
  • InChI=1S/C19H17ClN2O4/c1-11-15(10-18(23)21-25)16-9-14(26-2)7-8-17(16)22(11)19(24)12-3-5-13(20)6-4-12/h3-9,25H,10H2,1-2H3,(H,21,23)
  • Key:AJRNYCDWNITGHF-UHFFFAOYSA-N
  (what is this?)  (verify)

Oxametacin (or oxamethacin) is a non-steroidal anti-inflammatory drug.

Hydrolysis of the amide group is one of the synthetic pathways to Deboxamet (ChemDrug).

References

  1. Schweiger J (1999). "Oxametacin". In von Bruchhausen F, Ebel S, Hackenthal E, Holzgrabe U (eds.). Hagers Handbuch der Pharmazeutischen Praxis: Stoffe L-Z Folgeband 5 (in German) (5th, vollständig neubearbeitete Auflage ed.). Berlin, Heidelberg. pp. 367–368. ISBN 978-3-642-58388-9.{{cite book}}: CS1 maint: location missing publisher (link)
Non-steroidal anti-inflammatory drugs (NSAIDs) (primarily M01A and M02A, also N02BA)
pyrazolones /
pyrazolidines
salicylates
acetic acid derivatives
and related substances
oxicams
propionic acid
derivatives (profens)
n-arylanthranilic
acids (fenamates)
COX-2 inhibitors
(coxibs)
other
NSAID
combinations
Key: underline indicates initially developed first-in-class compound of specific group; WHO-Essential Medicines; withdrawn drugs; veterinary use.
Prostanoid signaling modulators
Receptor
(ligands)
DP (D2)Tooltip Prostaglandin D2 receptor
DP1Tooltip Prostaglandin D2 receptor 1
DP2Tooltip Prostaglandin D2 receptor 2
EP (E2)Tooltip Prostaglandin E2 receptor
EP1Tooltip Prostaglandin EP1 receptor
EP2Tooltip Prostaglandin EP2 receptor
EP3Tooltip Prostaglandin EP3 receptor
EP4Tooltip Prostaglandin EP4 receptor
Unsorted
FP (F)Tooltip Prostaglandin F receptor
IP (I2)Tooltip Prostacyclin receptor
TP (TXA2)Tooltip Thromboxane receptor
Unsorted
Enzyme
(inhibitors)
COX
(PTGS)
PGD2STooltip Prostaglandin D synthase
PGESTooltip Prostaglandin E synthaseHQL-79
PGFSTooltip Prostaglandin F synthaseBimatoprost
PGI2STooltip Prostacyclin synthaseTranylcypromine
TXASTooltip Thromboxane A synthase
Others
See also
Receptor/signaling modulators
Leukotriene signaling modulators


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