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'''Isoaminile''' was discovered by Hoechst AG in the 1950s<ref>DE Patent 1034649</ref>. It is used under the trade0anme ('''Peracon''') as an ] and is structurally related to ]. ] effects have been noted from doses approximately 300 mg and above. The normal therapeutic dose is 40-80 mg of the cyclamate salt not to exceed five doses in a 24-hour period. In addition to central antitussive effects it is also an ], exhibiting both ] and ] actions. '''Isoaminile''' was discovered by Hoechst AG in the 1950s<ref>DE Patent 1034649</ref>. It is used under the trade-name ('''Peracon''') as an ] and is structurally related to ]. ] effects have been noted from doses approximately 300 mg and above. The normal therapeutic dose is 40-80 mg of the cyclamate salt not to exceed five doses in a 24-hour period. In addition to central antitussive effects it is also an ], exhibiting both ] and ] actions.




Revision as of 22:56, 18 November 2011

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Pharmaceutical compound
Isoaminile
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
IUPAC name
  • 4-(dimethylamino)-2-isopropyl-2-phenylpentanenitrile
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.000.940 Edit this at Wikidata
Chemical and physical data
FormulaC16H24N2
Molar mass244.375 g/mol g·mol
3D model (JSmol)
SMILES
  • N#CC(c1ccccc1)(C(C)C)CC(N(C)C)C
InChI
  • InChI=1S/C16H24N2/c1-13(2)16(12-17,11-14(3)18(4)5)15-9-7-6-8-10-15/h6-10,13-14H,11H2,1-5H3
  • Key:WFLSCFISQHLEED-UHFFFAOYSA-N
  (verify)

Isoaminile was discovered by Hoechst AG in the 1950s. It is used under the trade-name (Peracon) as an antitussive and is structurally related to methadone. Psychedelic effects have been noted from doses approximately 300 mg and above. The normal therapeutic dose is 40-80 mg of the cyclamate salt not to exceed five doses in a 24-hour period. In addition to central antitussive effects it is also an anticholinergic, exhibiting both antimuscarinic and antinicotinic actions.


References

  1. DE Patent 1034649


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