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Isoaminile

Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	R05DB04 (WHO)
Identifiers
IUPAC name 4-(dimethylamino)-2-isopropyl-2-phenylpentanenitrile
CAS Number	77-51-0
PubChem CID	6481
ChemSpider	6236
UNII	R4823W2PQL
KEGG	D08088
CompTox Dashboard (EPA)	DTXSID5057830
ECHA InfoCard	100.000.940
Chemical and physical data
Formula	C16H24N2
Molar mass	244.375 g/mol g·mol
3D model (JSmol)	Interactive image
SMILES N#CC(c1ccccc1)(C(C)C)CC(N(C)C)C
InChI InChI=1S/C16H24N2/c1-13(2)16(12-17,11-14(3)18(4)5)15-9-7-6-8-10-15/h6-10,13-14H,11H2,1-5H3 Key:WFLSCFISQHLEED-UHFFFAOYSA-N
(verify)

Isoaminile was discovered by Hoechst AG in the 1950s. It is used under the trade0anme (Peracon) as an antitussive and is structurally related to methadone. Psychedelic effects have been noted from doses approximately 300 mg and above. The normal therapeutic dose is 40-80 mg of the cyclamate salt not to exceed five doses in a 24-hour period. In addition to central antitussive effects it is also an anticholinergic, exhibiting both antimuscarinic and antinicotinic actions.

References

1. DE Patent 1034649

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