Misplaced Pages

Glicaramide

Clinical data
ATC code	None
Identifiers
IUPAC name N-ethyl]-1-ethyl-3-methyl-4-(3-methylbutoxy)pyrazolopyridine-5-carboxamide
CAS Number	36980-34-4
PubChem CID	65799
ChemSpider	59215
UNII	UK5SR22C8Q
ChEMBL	ChEMBL2106430
CompTox Dashboard (EPA)	DTXSID60190471
Chemical and physical data
Formula	C30H42N6O5S
Molar mass	598.76 g·mol
3D model (JSmol)	Interactive image
SMILES C0CCCCC0NC(=O)NS(=O)(=O)c1ccc(cc1)CCNC(=O)c2cnc3n(CC)nc(C)c3c2OCCC(C)C

Glicaramide (SQ-65993) is an orally bioavailable anti-diabetic medication. It has a similar potency as glibenclamide (glyburide) in the class of medication known as sulfonylureas. Its structure is similar since it has a cyclic acyl group which replaces the latter's 2-methoxy-5-chlorobenzyl. Same as glibenclamide, it is classified as a second-generation sulfonylurea. It may have more pronounced extra-pancreatic effects than glibenclamide or tolbutamide.

See also

• Glibenclamide

References

1. Höhn H, Polacek I, Schulze E (December 1973). "Potential antidiabetic agents. Pyrazolo(3,4-b)pyridines". Journal of Medicinal Chemistry. 16 (12): 1340–6. doi:10.1021/jm00270a006. PMID 4358224.
2. ^ Sarges R (1981). "Hypoglycemic Drugs". In Ellis GP, West GB (eds.). Progress in Medicinal Chemistry. Vol. 18. Elsevier Science. p. 202. ISBN 0-444-80345-9. Archived from the original on 2023-01-28. Retrieved 2016-10-18.

This drug article relating to the gastrointestinal system is a stub. You can help Misplaced Pages by expanding it.

• v
• t
• e

• Drugs not assigned an ATC code
• Potassium channel blockers
• Diuretics
• 1-(Benzenesulfonyl)-3-cyclohexylureas
• Carboxamides
• Phenol ethers
• Pyrazolopyridines
• Isopentyl compounds
• Gastrointestinal system drug stubs