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T-1152

Names
Other names TL-1178 Stedman's meta compound
Identifiers
CAS Number	3983-39-9
3D model (JSmol)	Interactive image
ChemSpider	18732
PubChem CID	19886
CompTox Dashboard (EPA)	DTXSID60960393
InChI InChI=1S/C11H16N2O2.HI/c1-12-11(14)15-10-7-5-6-9(8-10)13(2,3)4;/h5-8H,1-4H3;1HKey: MIAARRZWMRMHIS-UHFFFAOYSA-N
SMILES CNC(=O)OC1=CC=CC(=C1)(C)(C)C.
Hazards
Lethal dose or concentration (LD, LC):
LD50 (median dose)	270 μg/kg (subcutaneous, mice) 115 μg/kg (intravenous, mice) 260 μg/kg (subcutaneous, rabbits)
LDLo (lowest published)	2.5 mg/kg (oral, mice)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Infobox references

T-1152 is a quaternary carbamate anticholinesterase. It is synthesized by reaction of m-dimethylaminophenol with methyl isocyanate, followed by quaternization with methyl iodide. Since T-1152 is toxic by ingestion, it was patented as a rodenticide in 1932.

The chloride and methylsulfate salt of T-1152 is T-1690 (TL-1226) and AR-13, respectively.

See also

• Neostigmine
• T-1123
• T-1194
• TL-599
• TL-1238

References

1. ^ Chemical Warfare Agents, and Related Chemical Problems. Parts I-II. 1958.
2. ^ "Product for destroying animals".
3. Stedman, Edgar (1 January 1926). "Studies on the Relationship between Chemical Constitution and Physiological Action". Biochemical Journal. 20 (4): 719–734. doi:10.1042/bj0200719. PMC 1251776. PMID 16743713.

• Carbamate nerve agents
• Acetylcholinesterase inhibitors
• Aromatic carbamates
• Phenol esters
• Quaternary ammonium compounds
• Iodides
• Rodenticides