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Dimefox

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Dimefox
Names
IUPAC name N--N-methylmethanamine
Other names TL-792
T-2002
Identifiers
CAS Number
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.003.706 Edit this at Wikidata
EC Number
  • 204-076-8
KEGG
PubChem CID
UNII
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C4H12FN2OP/c1-6(2)9(5,8)7(3)4/h1-4H3Key: PGJBQBDNXAZHBP-UHFFFAOYSA-N
  • InChI=1/C4H12FN2OP/c1-6(2)9(5,8)7(3)4/h1-4H3Key: PGJBQBDNXAZHBP-UHFFFAOYAM
SMILES
  • CN(C)P(=O)(N(C)C)F
Properties
Chemical formula C4H12FN2OP
Molar mass 154.125 g·mol
Appearance colourless liquid
Density 1.11 g·mL
Solubility in water 14.8 g·L
Vapor pressure 14663 mPa
Henry's law
constant
 (kH)
2.28·10 atm·m·mol
Pharmacology
Routes of
administration
inhalation and dermal contact
Legal status
  • UK: Banned
  • US: Banned
Hazards
Occupational safety and health (OHS/OSH):
Main hazards Highly Toxic
GHS labelling:
Pictograms GHS06: Toxic
Signal word Danger
Hazard statements H300, H310
Precautionary statements P262, P264, P270, P280, P301+P310, P302+P350, P310, P321, P322, P330, P361, P363, P405, P501
Lethal dose or concentration (LD, LC):
LD50 (median dose) 2 mg/kg (oral, mice)
1 mg/kg (oral, rats)
3 mg/kg (intravenous, rabbits)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). ☒verify (what is  ?) Infobox references
Chemical compound

Dimefox, also known as TL-792 or T-2002, is a highly toxic organophosphate insecticide. In its pure form it is a colourless liquid with a fishy odour. Dimefox was first produced in 1940 by the group of Gerhard Schrader in Germany. It was historically used as a pesticide, but has been deemed obsolete or discontinued for use by the World Health Organization due to being an inhibitor of acetylcholinesterase. It is not guaranteed that all commercial use of this compound ceased, but in most countries it is no longer registered for use as a pesticide. It is considered an extremely hazardous substance as defined by the United States Emergency Planning and Community Right-to-Know Act.

See also

References

  1. ^ Chemical Warfare Agents, and Related Chemical Problems. Parts I-II. 1958.
  2. "Dimefox".
  3. "IUPAC FOOTPRINT Pesticides Properties Database". Archived from the original on 2011-07-22. Retrieved 2011-04-06.
  4. the WHO recommended classification of pesticides by hazard and guidelines to classification 2009,
Blood agents
Blister agents
Arsenicals
  • Ethyldichloroarsine (ED)
  • Methyldichloroarsine (MD)
  • Phenyldichloroarsine (PD)
  • Lewisite (L)
  • Lewisite 2 (L2)
  • Lewisite 3 (L3)
  • Sulfur mustards
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    Metabolites
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    Acetylcholine metabolism and transport modulators
    Enzyme
    (modulators)
    ChATTooltip Choline acetyltransferase
    AChETooltip Acetylcholinesterase
    BChETooltip Butyrylcholinesterase
    Transporter
    (modulators)
    CHTTooltip Choline transporter
    VAChTTooltip Vesicular acetylcholine transporter
    Release
    (modulators)
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    Enhancers
    See also
    Receptor/signaling modulators
    Muscarinic acetylcholine receptor modulators
    Nicotinic acetylcholine receptor modulators
    Neurotoxins
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