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HOXC9

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Protein-coding gene in the species Homo sapiens
HOXC9
Available structures
PDBOrtholog search: PDBe RCSB
List of PDB id codes

2LP0, 2MSY

Identifiers
AliasesHOXC9, HOX3, HOX3B, homeobox C9
External IDsOMIM: 142971; MGI: 96199; HomoloGene: 130558; GeneCards: HOXC9; OMA:HOXC9 - orthologs
Gene location (Human)
Chromosome 12 (human)
Chr.Chromosome 12 (human)
Chromosome 12 (human)Genomic location for HOXC9Genomic location for HOXC9
Band12q13.13Start53,994,895 bp
End54,003,337 bp
Gene location (Mouse)
Chromosome 15 (mouse)
Chr.Chromosome 15 (mouse)
Chromosome 15 (mouse)Genomic location for HOXC9Genomic location for HOXC9
Band15 F3|15 58.04 cMStart102,884,874 bp
End102,893,531 bp
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • Achilles tendon

  • gastrocnemius muscle

  • testicle

  • gonad

  • vastus lateralis muscle

  • subcutaneous adipose tissue

  • tibialis anterior muscle

  • popliteal artery

  • tibial arteries

  • skin of leg
Top expressed in
  • tail of embryo

  • female urethra

  • ankle joint

  • extensor digitorum longus muscle

  • plantaris muscle

  • muscle of thigh

  • serosa of urinary bladder

  • quadriceps femoris muscle

  • soleus muscle

  • epithelium of female urethra
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

3225

15427

Ensembl

ENSG00000180806

ENSMUSG00000036139

UniProt

P31274

P09633

RefSeq (mRNA)

NM_006897

NM_008272

RefSeq (protein)

NP_008828

NP_032298

Location (UCSC)Chr 12: 53.99 – 54 MbChr 15: 102.88 – 102.89 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Homeobox protein Hox-C9 is a protein that in humans is encoded by the HOXC9 gene.

Function

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12.

See also

References

  1. ^ GRCh38: Ensembl release 89: ENSG00000180806Ensembl, May 2017
  2. ^ GRCm38: Ensembl release 89: ENSMUSG00000036139Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. McAlpine PJ, Shows TB (July 1990). "Nomenclature for human homeobox genes". Genomics. 7 (3): 460. doi:10.1016/0888-7543(90)90186-X. PMID 1973146.
  6. ^ "Entrez Gene: HOXC9 homeobox C9".

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


Transcription factors and intracellular receptors
(1) Basic domains
(1.1) Basic leucine zipper (bZIP)
(1.2) Basic helix-loop-helix (bHLH)
Group A
Group B
Group C
bHLH-PAS
Group D
Group E
Group F
bHLH-COE
(1.3) bHLH-ZIP
(1.4) NF-1
(1.5) RF-X
(1.6) Basic helix-span-helix (bHSH)
(2) Zinc finger DNA-binding domains
(2.1) Nuclear receptor (Cys4)
subfamily 1
subfamily 2
subfamily 3
subfamily 4
subfamily 5
subfamily 6
subfamily 0
(2.2) Other Cys4
(2.3) Cys2His2
(2.4) Cys6
(2.5) Alternating composition
(2.6) WRKY
(3) Helix-turn-helix domains
(3.1) Homeodomain
Antennapedia
ANTP class
protoHOX
Hox-like
metaHOX
NK-like
other
(3.2) Paired box
(3.3) Fork head / winged helix
(3.4) Heat shock factors
(3.5) Tryptophan clusters
(3.6) TEA domain
  • transcriptional enhancer factor
(4) β-Scaffold factors with minor groove contacts
(4.1) Rel homology region
(4.2) STAT
(4.3) p53-like
(4.4) MADS box
(4.6) TATA-binding proteins
(4.7) High-mobility group
(4.9) Grainyhead
(4.10) Cold-shock domain
(4.11) Runt
(0) Other transcription factors
(0.2) HMGI(Y)
(0.3) Pocket domain
(0.5) AP-2/EREBP-related factors
(0.6) Miscellaneous
see also transcription factor/coregulator deficiencies


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