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IFI35
Identifiers
Aliases	IFI35, IFP35, interferon induced protein 35
External IDs	OMIM: 600735; MGI: 1917360; HomoloGene: 4040; GeneCards: IFI35; OMA:IFI35 - orthologs
Gene location (Human) Chr. Chromosome 17 (human) Band 17q21.31 Start 43,006,740 bp End 43,014,456 bp
Gene location (Mouse) Chr. Chromosome 11 (mouse) Band 11|11 D Start 101,339,233 bp End 101,349,524 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in granulocyte monocyte decidua right adrenal gland right adrenal cortex left adrenal cortex mucosa of transverse colon apex of heart spleen gallbladder Top expressed in right lung lobe endothelial cell of lymphatic vessel carotid body iris conjunctival fornix lacrimal gland submandibular gland blood Paneth cell epithelium of stomach More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding Cellular component cytosol nucleus Biological process type I interferon signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 3430 70110 Ensembl ENSG00000068079 ENSMUSG00000010358 UniProt P80217 Q9D8C4 RefSeq (mRNA) NM_005533 NM_001330230 NM_027320 RefSeq (protein) NP_001317159 NP_005524 NP_081596 Location (UCSC) Chr 17: 43.01 – 43.01 Mb Chr 11: 101.34 – 101.35 Mb PubMed search
Wikidata
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Interferon-induced 35 kDa protein is a protein that in humans is encoded by the IFI35 gene.

Interactions

IFI35 has been shown to interact with NMI and BATF.

References

1. ^ GRCh38: Ensembl release 89: ENSG00000068079 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000010358 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: IFI35 interferon-induced protein 35".
6. Chen J, Shpall RL, Meyerdierks A, Hagemeier M, Böttger EC, Naumovski L (November 2000). "Interferon-inducible Myc/STAT-interacting protein Nmi associates with IFP 35 into a high molecular mass complex and inhibits proteasome-mediated degradation of IFP 35". The Journal of Biological Chemistry. 275 (46): 36278–84. doi:10.1074/jbc.M006975200. PMID 10950963.
7. Wang X, Johansen LM, Tae HJ, Taparowsky EJ (December 1996). "IFP 35 forms complexes with B-ATF, a member of the AP1 family of transcription factors". Biochemical and Biophysical Research Communications. 229 (1): 316–22. doi:10.1006/bbrc.1996.1799. PMID 8954125.

Further reading

• Brown MA, Jones KA, Nicolai H, Bonjardim M, Black D, McFarlane R, de Jong P, Quirk JP, Lehrach H, Solomon E (May 1995). "Physical mapping, cloning, and identification of genes within a 500-kb region containing BRCA1". Proceedings of the National Academy of Sciences of the United States of America. 92 (10): 4362–6. Bibcode:1995PNAS...92.4362B. doi:10.1073/pnas.92.10.4362. PMC 41944. PMID 7753812.
• Bange FC, Vogel U, Flohr T, Kiekenbeck M, Denecke B, Böttger EC (January 1994). "IFP 35 is an interferon-induced leucine zipper protein that undergoes interferon-regulated cellular redistribution". The Journal of Biological Chemistry. 269 (2): 1091–8. doi:10.1016/S0021-9258(17)42225-3. PMID 8288566.
• Smith TM, Lee MK, Szabo CI, Jerome N, McEuen M, Taylor M, Hood L, King MC (November 1996). "Complete genomic sequence and analysis of 117 kb of human DNA containing the gene BRCA1". Genome Research. 6 (11): 1029–49. doi:10.1101/gr.6.11.1029. PMID 8938427.
• Wang X, Johansen LM, Tae HJ, Taparowsky EJ (December 1996). "IFP 35 forms complexes with B-ATF, a member of the AP1 family of transcription factors". Biochemical and Biophysical Research Communications. 229 (1): 316–22. doi:10.1006/bbrc.1996.1799. PMID 8954125.
• Zhou X, Liao J, Meyerdierks A, Feng L, Naumovski L, Bottger EC, Omary MB (July 2000). "Interferon-alpha induces nmi-IFP35 heterodimeric complex formation that is affected by the phosphorylation of IFP35". The Journal of Biological Chemistry. 275 (28): 21364–71. doi:10.1074/jbc.M003177200. PMID 10779520.
• Chen J, Shpall RL, Meyerdierks A, Hagemeier M, Böttger EC, Naumovski L (November 2000). "Interferon-inducible Myc/STAT-interacting protein Nmi associates with IFP 35 into a high molecular mass complex and inhibits proteasome-mediated degradation of IFP 35". The Journal of Biological Chemistry. 275 (46): 36278–84. doi:10.1074/jbc.M006975200. PMID 10950963.
• Chen J, Naumovski L (February 2002). "Intracellular redistribution of interferon-inducible proteins Nmi and IFP 35 in apoptotic cells". Journal of Interferon & Cytokine Research. 22 (2): 237–43. doi:10.1089/107999002753536211. PMID 11911807.
• Izmailova E, Bertley FM, Huang Q, Makori N, Miller CJ, Young RA, Aldovini A (February 2003). "HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages". Nature Medicine. 9 (2): 191–7. doi:10.1038/nm822. PMID 12539042. S2CID 26145639.
• Gevaert K, Goethals M, Martens L, Van Damme J, Staes A, Thomas GR, Vandekerckhove J (May 2003). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides". Nature Biotechnology. 21 (5): 566–9. doi:10.1038/nbt810. PMID 12665801. S2CID 23783563.
• Zhang L, Tang Y, Tie Y, Tian C, Wang J, Dong Y, Sun Z, He F (May 2007). "The PH domain containing protein CKIP-1 binds to IFP35 and Nmi and is involved in cytokine signaling". Cellular Signalling. 19 (5): 932–44. doi:10.1016/j.cellsig.2006.11.002. PMID 17197158.

External links

• IFI35+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

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